Functional substrate mapping characteristics during sinus rhythm predicts critical isthmus of reentrant atrial tachycardia

Hikmet Yorgun; Cem Çöteli; Gül Sinem Kılıç; Burak Sezenöz; Muhammet Dural; Ahmet Hakan Ateş; Kudret Aytemir

doi:10.1111/jce.15961

June 3, 2023Journal of Cardiovascular ElectrophysiologyOpen Access

Functional substrate mapping characteristics during sinus rhythm predicts critical isthmus of reentrant atrial tachycardia

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Why the study?

Does functional substrate mapping during sinus rhythm predict the critical isthmus of atrial tachycardia?

Structured PICO

Does functional substrate mapping during sinus rhythm predict the critical isthmus of atrial tachycardia?

P

Population

Patients with atrial tachycardia (AT) and underlying atrial scar

I

Intervention

Functional substrate mapping (FSM) during sinus rhythm

O

Outcome

Prediction of the critical isthmus (CI) of atrial tachycardiasurrogate

Functional substrate mapping during sinus rhythm can identify deceleration zones with slow conduction to predict the critical isthmus of atrial tachycardia, potentially guiding tailored ablation strategies.

Implication

May support mapping-guided ablation in atrial tachycardia; hypothesis-generating pending prospective validation.

Abstract

Our findings demonstrated the utility of FSM during sinus rhythm to predict the CI of AT. DZs displayed continuous-fragmented signal morphology with slow conduction which may guide to tailor ablation strategy in case of underlying atrial scar.