Why the study?
Does viral gene transfer of Bcl-2 protect against chronic postischemic heart failure?
Does viral gene transfer of Bcl-2 protect against chronic postischemic heart failure?
Viral gene transfer of Bcl-2 preserves LV function and reduces ventricular remodeling at 6 weeks in a postischemic heart failure model.
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Bcl-2 gene transfer merits further preclinical optimization for postischemic remodeling; leaves open translation to human heart failure.
Chatterjee et al. (2002) studied this question.
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