Why the study?
Does the choice of anticoagulation strategy improve maternal and fetal outcomes in pregnant women with mechanical heart valves?
Does the choice of anticoagulation strategy improve maternal and fetal outcomes in pregnant women with mechanical heart valves?
In pregnant women with mechanical heart valves, there is a trade-off between maternal and fetal outcomes, with VKAs minimizing maternal complications and LMWH maximizing livebirths.
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Emphasizes individualized anticoagulation decisions in pregnant women with mechanical valves; leaves open optimal strategy pending randomized data.
D’Souza et al. (2017) studied this question.
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