Why the study?
Does the choice of anticoagulation strategy improve maternal and fetal outcomes in pregnant women with mechanical heart valves?
Population
Pregnant women with mechanical heart valves
Comparison
Anticoagulation strategies including Vitamin K… vs Alternative anticoagulation strategies compared…
Design
Meta-analysis
Follow-up
Pregnancy
Authors
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Emphasizes individualized anticoagulation decisions in pregnant women with mechanical valves; leaves open optimal strategy pending randomized data.
Does the choice of anticoagulation strategy improve maternal and fetal outcomes in pregnant women with mechanical heart valves?
In pregnant women with mechanical heart valves, there is a trade-off between maternal and fetal outcomes, with VKAs minimizing maternal complications and LMWH maximizing livebirths.
D’Souza et al. (2017) studied this question.
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