Why the study?
Can monoclonal antibodies against Seneca Valley virus be used to develop a specific diagnostic test for SVV infection in pigs?
Population
Mice immunized with binary ethylenimine (BEI)-inactivated SVV and pigs experimentally inoculated with SVV.
Comparison
Generation of 5 monoclonal antibodies against… vs Indirect isotype ELISA and virus neutralization…
Design
Preclinical
Follow-up
57 days
Authors
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SVV cELISA supports serological detection tool development in pigs; leaves open field validation and clinical adoption.
Can monoclonal antibodies against Seneca Valley virus be used to develop a specific diagnostic test for SVV infection in pigs?
The developed panel of SVV-specific monoclonal antibodies and cELISA provides a valuable tool for the specific identification of SVV antigen and serological detection of SVV infection in pigs.
Yang et al. (2011) studied this question.
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