August 1, 2023Open HeartOpen Access

Clinical Frailty Scale as a predictor of adverse outcomes following aortic valve replacement: a systematic review and meta-analysis

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Why the study?

Does frailty, as determined by the Clinical Frailty Scale, predict 12-month mortality in elderly patients undergoing aortic valve replacement?

Structured PICO

Does frailty, as determined by the Clinical Frailty Scale, predict 12-month mortality in elderly patients undergoing aortic valve replacement?

Population

Elderly patients undergoing aortic valve interventions (TAVI or SAVR)

Intervention

Clinical Frailty Scale (CFS) assessment for frailty

Outcome

Mortality risk in the 12 months following either TAVI or SAVRhard clinical

The Clinical Frailty Scale is a valuable preoperative assessment tool that predicts 12-month mortality risk in elderly patients undergoing TAVI or SAVR.

Implication

Supports preoperative CFS use for mortality risk stratification before TAVI or SAVR; reinforces its prognostic value in pooled data.

Abstract

Frailty, as determined by the CFS, was associated with an increased mortality risk in the 12 months following either TAVI or SAVR. These data would support its use in the preoperative assessment of elderly patients undergoing aortic valve interventions.