Key result
Higher Clinical Frailty Scale grade was independently associated with increased 1-year mortality after balloon aortic valvuloplasty (OR 1.75), with severely frail patients experiencing a 65.2% mortality rate.
Why the study?
While the Clinical Frailty Scale predicts late mortality after transcatheter aortic valve replacement, its association with 1-year mortality after balloon aortic valvuloplasty was evaluated.
Does the clinical frailty scale (CFS) predict 1-year mortality in elderly patients with severe aortic stenosis undergoing balloon aortic valvuloplasty?
Cohort (n=127)
No
Does the clinical frailty scale (CFS) predict 1-year mortality in elderly patients with severe aortic stenosis undergoing balloon aortic valvuloplasty?
Odds Ratio: 1.75 (95% CI 1.17–2.62)
p-value: p=0.007
Severe frailty (CFS ≥7) combined with high surgical risk (STS score ≥8.7%) identifies a subgroup of elderly patients with severe aortic stenosis who have extremely poor 1-year survival (81.3% mortality) after balloon aortic valvuloplasty.
CFS may stratify 1-year mortality risk after BAV; leaves open prospective validation before guiding decisions.
Background:The clinical frailty scale (CFS) predicts late mortality in patients undergoing transcatheter aortic valve replacement. We evaluated the CFS and other parameters associated with 1-year mortality after balloon aortic valvuloplasty (BAV).
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Hamana et al. (2020) conducted a cohort in Severe aortic stenosis (n=127). Clinical Frailty Scale (CFS) vs. Lower CFS grades was evaluated on 1-year mortality (OR 1.75, 95% CI 1.17-2.62, p=0.007). Higher Clinical Frailty Scale grade was independently associated with increased 1-year mortality after balloon aortic valvuloplasty (OR 1.75), with severely frail patients experiencing a 65.2% mortality rate.
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