Why the study?
Do different strains of Coxsackievirus B1 differ in their ability to induce innate immune responses in PBMCs?
Do different strains of Coxsackievirus B1 differ in their ability to induce innate immune responses in PBMCs?
Enterovirus-induced immune activation depends on the specific virus strain, which may modulate the course of infection and play a role in the pathogenesis of chronic immune-mediated diseases such as cardiomyopathies.
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Strain variation in CBV1 IFN-α induction does not alter management; leaves open its role in cardiomyopathy pathogenesis.
Hämäläinen et al. (2014) studied this question.
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