Why the study?
What are the determinants of left ventricular mass in obese individuals without additional cardiovascular risk factors?
What are the determinants of left ventricular mass in obese individuals without additional cardiovascular risk factors?
Increases in lean body mass, left ventricular stroke volume, and visceral fat mass are the primary drivers of left ventricular hypertrophy in obese patients lacking other cardiovascular risk factors.
LV mass assessment in low-risk obesity may prioritize lean mass and stroke volume over total adiposity; hypothesis-generating pending longitudinal confirmation.
The left ventricular hypertrophic response to obesity in the absence of additional cardiovascular risk factors is mainly attributable to increases in lean body mass, LV stroke volume and visceral fat mass. In view of the well documented link between obesity, left ventricular hypertrophy and mortality, these findings have potentially important prognostic and therapeutic implications for primary and secondary prevention.
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Rider et al. (2009) studied this question.
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