Why the study?
Are there gender-related differences in muscle sympathetic nerve activity and blood flow in normal subjects?
Population
68 normal subjects (34 women and 34 men), matched for age, BMI (body mass index), and waist circumference.
Design
Cross-sectional
Authors
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May explain lower CV event rates in women; hypothesis-generating for sex differences in sympathetic regulation.
Are there gender-related differences in muscle sympathetic nerve activity and blood flow in normal subjects?
Women exhibit lower central sympathetic neural output and a blunted vasoconstrictor response compared to men, providing a potential physiological mechanism for their lower incidence of cardiovascular events.
Hogarth et al. (2007) studied this question.
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