Why the study?
How does left atrial substrate change over time following pulmonary vein isolation in patients with atrial fibrillation?
Population
Patients with atrial fibrillation undergoing pulmonary vein isolation
Design
Cohort
Authors
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May support adaptive LVZ ablation timing post-PVI; leaves open prospective validation of dynamic substrate-guided strategies.
How does left atrial substrate change over time following pulmonary vein isolation in patients with atrial fibrillation?
The dynamic nature of left atrial substrate following pulmonary vein isolation suggests that low-voltage zone (LVZ)-based ablation strategies may need to account for substrate regression or progression over time.
Marcon et al. (2023) studied this question.
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