The lifetime risk of developing atrial fibrillation is substantial (1 in 4 for adults 40 years and older), highlighting a major public health burden.
Substantial lifetime AF risk persists without prior HF/MI; leaves open targeted prevention trials in observational cohorts.
Lifetime risks for development of AF are 1 in 4 for men and women 40 years of age and older. Lifetime risks for AF are high (1 in 6), even in the absence of antecedent congestive heart failure or myocardial infarction. These substantial lifetime risks underscore the major public health burden posed by AF and the need for further investigation into predisposing conditions, preventive strategies, and more effective therapies.
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Lloyd‐Jones et al. (2004) studied this question.
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