What question did this study set out to answer?

The aim is to identify factors influencing aortic valve calcification in the elderly population.

July 1, 1994European Heart Journal

Factors associated with calcific aortic valve degeneration in the elderly

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Population

577 adults, comprising 501 individuals aged 75-86 years and 76 individuals aged 55-71 years.

Design

Cross-sectional

Authors

MLM. LlNDROOSHelsinki University Hospital MKMarkku KupariCardiac Imaging JVJ. ValvanneHelsinki University Hospital

Discussion

Member takes

Implication

Highlights candidates for prospective trials; leaves open causality and should not yet change practice.

Key Points

The aim is to identify factors influencing aortic valve calcification in the elderly population.
Compared echocardiographic and Doppler characteristics of the aortic valve with clinical and biochemical predictors in 501 people aged 75-86 and 76 aged 55-71.
Conducted multivariate analysis to determine independent predictors of aortic valve calcification.
Age (HR 1.89, 95% CI 1.42-2.50, P=0.000) is a significant predictor of valve calcification.
Hypertension increases the risk of calcification (HR 1.74, 95% CI 1.19-2.55, P=0.005).
A decrease in body mass index correlates with calcification risk (HR 1.39, 95% CI 1.10-1.76, P=0.005).

Structured PICO

Population

577 adults, comprising 501 individuals aged 75-86 years and 76 individuals aged 55-71 years.

Outcome

Aortic valve calcification and valve stenosis assessed via echocardiographic and Doppler characteristicssurrogate

Older age, a history of hypertension, and lower body mass index (leanness) are independent predictors of senile aortic valve calcification.

Cite This Study

LlNDROOS et al. (1994) studied this question.

synapsesocial.com/papers/69d5718875589c71d767e2d2 https://doi.org/10.1093/oxfordjournals.eurheartj.a060602

Topics

Hypertension management

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Factors associated with calcific aortic valve degeneration in the elderly

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Factors associated with calcific aortic valve degeneration in the elderly

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Topics

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