Comparison of transcatheter aortic valve implantation with other approaches to treat aortic valve stenosis: a systematic review and meta-analysis

Fig. 1. PRISMA flow diagram modified from Moher et al. [13] Abbreviations: MT = medical therapy, PRISMA = Preferred Reporting Items for Systematic Reviews and Meta-Analyses, SAVR = surgical aortic valve replacement, TAVI = transcatheter aortic valve replacement

Fig. 2. Forest plot 30-day mortality TAVI versus SAVR including randomized controlled trials and observational studies with propensity matching. Abbreviations: CI = confidence interval, D+L = DerSimonian and Laird method, M-H = Mantel-Haenszel method, NOTION = Nordic Aortic Valve Intervention, OBSERVANT = Observational Study of Effectiveness of SAVR-TAVR Procedures for Severe Aortic Stenosis Treatment, PARTNER = Placement of Aortic Transcatheter Valves, RCT = randomized controlled trial, RR = relative risk, SAVR = surgical aortic valve replacement, SURTAVI = Surgical Replacement and Transcatheter Aortic Valve Implantation, TAVI = transcatheter-aortic valve replacement, US = United States

Fig. 3. Forest-plot 1-year mortality TAVI versus SAVR including randomized controlled trials and observational studies with propensity matching. Abbreviations: CI = confidence interval, D+L = DerSimonian and Laird method, M-H = Mantel-Haenszel method, NOTION = Nordic Aortic Valve Intervention, OBSERVANT = Observational Study of Effectiveness of SAVR-TAVR Procedures for Severe Aortic Stenosis Treatment, PARTNER = Placement of Aortic Transcatheter Valves, RCT = randomized controlled trial, RR = relative risk, SAVR = surgical aortic valve replacement, SURTAVI = Surgical Replacement and Transcatheter Aortic Valve Implantation, TAVI = transcatheter-aortic valve replacement, US = United States

Fig. 4. Results from random-effects meta-analysis comparing TAVI with SAVR and including randomized controlled trials and observational studies. Abbreviations: CI = confidence interval, k = number of studies, n = number of patients, PAR = paravalvular aortic regurgitation, SAVR = surgical aortic valve replacement, TAVI = transcatheter-aortic valve replacement, TIA = transient ischemic attack