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February 14, 2015Circulation Arrhythmia and Electrophysiology190 citations

Core Isolation of Critical Arrhythmia Elements for Treatment of Multiple Scar-Based Ventricular Tachycardias

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WTWendy S. TzouDFDavid S. FrankelTHTimothy Hegeman

Structured PICO

Does core isolation of critical arrhythmia elements improve long-term success in patients with multiple or unmappable scar-based ventricular tachycardias?

P
Population
Patients with multiple or unmappable scar-based ventricular tachycardias
I
Intervention
Core Isolation (CI) of critical arrhythmia elements
O
Outcome
Exit block within the isolated area and long-term successsurrogate

Core isolation is a novel ablation strategy that targets suspected VT isthmus surrogates to achieve exit block, potentially improving long-term success in patients with multiple or unmappable scar-based VTs.

Abstract

CI is a novel strategy with a discrete and measurable end point beyond VT inducibility to treat patients with multiple or unmappable VTs. The CI region can be selected based on standard characterization of suspected VT isthmus surrogates thus limiting ablation target size. Exit block within the isolated area is achievable in most and may further improve long-term success.

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Cite This Study

Tzou et al. (2015) studied this question.

synapsesocial.com/papers/69d572cd75589c71d767e7d4https://doi.org/10.1161/circep.114.002310
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Linear Ablation Lesions for Control of Unmappable Ventricular Tachycardia in Patients With Ischemic and Nonischemic Cardiomyopathy2000 · 1,225 citations
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  5. 5Tachycardia-Related Channel in the Scar Tissue in Patients With Sustained Monomorphic Ventricular Tachycardias2004 · 264 citations