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July 22, 2010Pharmacoepidemiology and Drug Safety138 citationsOpen Access

Risk of serious ventricular arrhythmia and sudden cardiac death in a cohort of users of domperidone: a nested case‐control study

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CJCatherine B. JohannesCVCristina Varas‐LorenzoLMLisa J. McQuay

Structured PICO

Does domperidone increase the risk of serious ventricular arrhythmia and sudden cardiac death?

P
Population
Cohort of users of domperidone
I
Intervention
Domperidone
O
Outcome
Serious ventricular arrhythmia (SVA) and sudden cardiac death (SCD)safety

Current use of domperidone is associated with an increased risk of serious ventricular arrhythmia and sudden cardiac death.

Abstract

The increased risk of SVA/SCD for current domperidone users remained after adjustment for multiple covariates. The risk may vary among subgroups of exposed individuals.

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Cite This Study

Johannes et al. (2010) studied this question.

synapsesocial.com/papers/69d572cf75589c71d767e7e9https://doi.org/10.1002/pds.2016
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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