Why the study?
Does depression increase cardiac mortality via decreased heart rate variability in post-MI patients?
Does depression increase cardiac mortality via decreased heart rate variability in post-MI patients?
Decreased heart rate variability provides a plausible mechanistic link between depression and increased cardiac mortality following myocardial infarction.
Supports integrated post-MI care targeting depression and HRV; extends RCT evidence for autonomic mediation of mortality risk.
We conclude that greater autonomic dysfunction, as reflected by decreased HRV, is a plausible mechanism linking depression to increased cardiac mortality in post-MI patients.
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Carney et al. (2001) studied this question.
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