Why the study?
Does contractility-guided lead implant optimize chronic paced ventricular function in patients with and without repaired congenital heart disease?
Does contractility-guided lead implant optimize chronic paced ventricular function in patients with and without repaired congenital heart disease?
Contractility-guided pacing lead implantation may optimize chronic ventricular function by tailoring the implant site to the individual patient.
May support individualized lead placement to optimize function; leaves open prospective validation across populations.
There is no single "sweet spot" for optimal ventricular pacing, and the best implant sites are patient and CHD variable. Current lead designs ensure chronic stability/performance regardless of site. Proactive contractility-guided pacing implant can optimize chronic paced ventricular function.
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Karpawich et al. (2014) studied this question.
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