Inherited ventricular arrhythmias and sudden death in young German shepherd dogs appear to be a primary arrhythmic disorder without structural cardiac pathology, with potential autonomic nervous system involvement.
Hypothesis-generating in canine model; leaves open autonomic mechanisms for human inherited arrhythmia research.
The cause of the inherited severe ventricular arrhythmias and sudden death in these young German shepherd dogs is still undetermined. A purely arrhythmic disorder is supported by the lack of cardiac pathology. Moreover, the window of vulnerability to ventricular arrhythmias and the age and circumstances of death invite speculation about the role of the autonomic nervous system.
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Möise et al. (1994) studied this question.
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