Literature review highlights diverse phytochemicals and therapeutic bioactivities in mango leaf extracts, indicating their potential utility in functional foods and pharmaceuticals.
Key Points
To comprehensively review the nutritional composition, phytochemical profile, and health-promoting biological activities of mango (Mangifera indica L.) leaves.
Narrative synthesis of published scientific literature examining the nutritional constituents and bioactive compounds in Mangifera indica leaves.
Evaluation of preclinical and in vitro experimental evidence documenting the pharmacologic mechanisms and therapeutic bioactivities of mango leaf extracts.
Identified rich concentrations of diverse phytochemicals in mango leaves, predominantly mangiferin, alongside phenolic acids, benzophenones, flavonoids, carotenoids, and tocopherols.
Demonstrated broad-spectrum bioactivities for mango leaf extracts, including antioxidant, anticancer, antidiabetic, antimicrobial, antiobesity, lipid-lowering, hepatoprotective, and antidiarrheal properties.
Highlighted the promising utility of mango leaves in functional food and pharmaceutical drug design, while noting that robust human clinical trials remain necessary to establish therapeutic efficacy.