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November 1, 1999The Journal of Immunology

Autoimmune Myocarditis Does Not Require B Cells for Antigen Presentation

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Authors

SMSusan MalkielFeinstein Institute for Medical Research SFStephen M. FactorGeneral Cardiology BDBetty DiamondFeinstein Institute for Medical Research

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Implication

B cell deficiency does not prevent myocarditis induction in this model; leaves open their role in human autoimmune disease.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Malkiel et al. (1999) studied this question.

synapsesocial.com/papers/69d71b27faf9bc6d3dbef02a https://doi.org/10.4049/jimmunol.163.10.5265

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Myosin-induced acute myocarditis is a T cell-mediated disease1991 · 348 citations
2B7 costimulation and autoantigen specificity enable B cells to activate autoreactive T cells1996 · 53 citations
3Involvement of T Lymphocytes in the Pathogenesis of Coxsackie Virus B3 Heart Disease1974 · 315 citations
4T cell development in B cell-deficient mice. IV. The role of B cells as antigen-presenting cells in vivo.1986 · 85 citations
5Cardiac myosin induces myocarditis in genetically predisposed mice.1987 · 525 citations