Why the study?
What is the risk and outcome of cerebral oedema developing during diabetic ketoacidosis in childhood?
What is the risk and outcome of cerebral oedema developing during diabetic ketoacidosis in childhood?
Cerebral edema is a significant complication of DKA in children, associated with substantial morbidity and mortality.
Cerebral oedema warrants ongoing clinical vigilance in childhood DKA; leaves open optimal prevention strategies from observational data.
This first large population based study of cerebral oedema complicating DKA has produced risk estimates which are more reliable and less susceptible to bias than those from previous studies. Our study indicates that cerebral oedema remains an important complication of DKA during childhood and is associated with significant morbidity and mortality. Little is known of the aetiology of cerebral oedema in this condition and we are currently undertaking a case control study to address this issue.
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Edge et al. (2001) studied this question.
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