Do obese hirsute PCOS patients have altered metabolic risk markers compared to weight-matched controls?
Obese hirsute PCOS patients exhibit lower adiponectin and ghrelin levels compared to weight-matched controls, suggesting a very high risk for metabolic syndrome.
Obese hirsute PCOS patients demonstrated significantly lower adiponectin levels than weight-matched controls suggesting a very high risk for the metabolic syndrome. Furthermore, ghrelin levels were decreased in hirsute PCOS patients and showed a significant, negative correlation with testosterone independent of body composition.
Glintborg et al. (Tue,) studied this question.