Why the study?
Do obese hirsute PCOS patients have altered metabolic risk markers compared to weight-matched controls?
Do obese hirsute PCOS patients have altered metabolic risk markers compared to weight-matched controls?
Obese hirsute PCOS patients exhibit lower adiponectin and ghrelin levels compared to weight-matched controls, suggesting a very high risk for metabolic syndrome.
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May signal heightened metabolic vulnerability in obese hirsute PCOS; hypothesis-generating and requires prospective validation before practice implications.
Obese hirsute PCOS patients demonstrated significantly lower adiponectin levels than weight-matched controls suggesting a very high risk for the metabolic syndrome. Furthermore, ghrelin levels were decreased in hirsute PCOS patients and showed a significant, negative correlation with testosterone independent of body composition.
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Glintborg et al. (2006) studied this question.
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