What question did this study set out to answer?

To review the underlying biological mechanisms, lifestyle risks, and genetic contributors to atrial fibrillation to guide effective prevention and management strategies.

December 21, 2021SHILAP Revista de lepidopterologíaOpen Access

Atrial Fibrillation: Pathogenesis, Predisposing Factors, and Genetics

View Full Paper

Ask AI

Bookmark

Why the study?

Identifying modifiable risk factors and preventive measures for AF may enhance community health and lower the high health-care cost burden associated with managing this prevalent arrhythmia.

Key Points

To review the underlying biological mechanisms, lifestyle risks, and genetic contributors to atrial fibrillation to guide effective prevention and management strategies.
Narrative review synthesizing epidemiological evidence and translational research on atrial fibrillation.
Evaluated pathophysiological factors, including tissue remodeling, sedentary behavior, dietary habits, and genetic predisposition.
Atrial fibrillation affects an estimated 33.5 million individuals globally, driving elevated rates of stroke, peripheral embolism, and death.
Electrical and structural remodeling of atrial tissue forms the primary pathogenic foundation for the arrhythmia, accelerated by unhealthful lifestyle factors and hereditary risk.

Design

Review article

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Outlines AF risk factors for prevention; leaves open prospective trials validating modifiable targets.

Cite This Study

Sagris et al. (2021) studied this question.

synapsesocial.com/papers/69d760ec086f9d6299f30bb1 https://doi.org/10.3390/ijms23010006

Topics

Atrial fibrillation Persistent AF management

View Full Paper

Ask AI

Bookmark

Atrial Fibrillation: Pathogenesis, Predisposing Factors, and Genetics

Key Points

Discussion

Implication

Cite This Study

Topics

Atrial Fibrillation: Pathogenesis, Predisposing Factors, and Genetics

Key Points

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider