Why the study?
Does visceral fat secrete inflammatory adipokines into the portal circulation in extremely obese humans?
Population
25 extremely obese subjects undergoing gastric bypass surgery
Design
Cross-sectional
Authors
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May link visceral adiposity to systemic inflammation; hypothesis-generating and requires prospective validation before clinical adoption.
Does visceral fat secrete inflammatory adipokines into the portal circulation in extremely obese humans?
Visceral fat secretes IL-6 into the portal circulation, providing a mechanistic link between abdominal obesity and systemic inflammation.
Fontana et al. (2007) studied this question.
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