The Pfam protein families database in 2019
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Overview
Database report demonstrates expansion to 17,929 protein families and structural integration, highlighting enhanced domain classification and contributor attribution.
Key Points
- To describe the updates, curation refinements, and structural integrations introduced in Pfam release 32.0.
- Cross-referenced entries with the Evolutionary Classification of Protein Domains (ECOD) and collaborated with RepeatsDB to refine tandem repeats.
- Mapped Pfam type definitions to the Sequence Ontology (SO) and connected database entry curation to author ORCID identifiers.
- Expanded the total database content to 17,929 protein families in release 32.0.
- Established 825 new families based on uncharacterized families from the ECOD database.
- Refined domain boundaries, functional annotations, and clan groupings across existing protein entries.
Cite This Study
El-Gebali et al. (2018) studied this question.