Is adiposity associated with altered levels of aldosterone and natriuretic peptides in patients with HFrEF?
In patients with HFrEF, greater adiposity is associated with higher aldosterone and lower B-type natriuretic peptide levels, suggesting adipose tissue influences the neurohumoral milieu.
Greater adiposity was associated with higher concentrations of aldosterone but lower levels of B-type natriuretic peptides in patients with HFrEF. Adipose tissue may influence the neurohumoral milieu in HFrEF, including the secretion of aldosterone.
Matsumoto et al. (Sat,) studied this question.