April 30, 2017European Journal of Heart Failure256 citationsOpen Access
View Full PaperPHysicians' Guideline Adherence is Associated with Better Prognosis in Outpatients with Heart Failure with Reduced Ejection Fraction: The QUALIFY International Registry
Structured PICO
Does good adherence to pharmacologic treatment guidelines improve clinical outcomes in outpatients with HFrEF?
P
Population
Outpatients with Heart Failure with Reduced Ejection Fraction (HFrEF) in the QUALIFY International Registry
I
Intervention
Good adherence to pharmacologic treatment guidelines for ACEIs, ARBs, BBs, MRAs and ivabradine (prescription of at least 50% of recommended dosages)
O
Outcome
clinical outcomes
Adherence to guideline-directed medical therapy at ≥50% of target doses is associated with improved short-term clinical outcomes in outpatients with HFrEF.
Abstract
Good adherence to pharmacologic treatment guidelines for ACEIs, ARBs, BBs, MRAs and ivabradine, with prescription of at least 50% of recommended dosages, was associated with better clinical outcomes during 6-month follow-up. Continuing global educational initiatives are needed to emphasise the importance of guideline recommendations for optimising drug therapy and prescribing evidence-based doses in clinical practice.