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August 26, 2013European Journal of Heart FailureOpen Access

Are Hospitalized or Ambulatory Patients with Heart Failure Treated in Accordance with European Society of Cardiology Guidelines? Evidence from 12 440 Patients of the ESC Heart Failure Long-Term Registry

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Why the study?

Are hospitalized or ambulatory patients with heart failure treated in accordance with European Society of Cardiology guidelines?

Population

12,440 hospitalized or ambulatory patients with acute or chronic heart failure from the ESC Heart Failure…

Design

Cohort

Authors

AMAldo P. MaggioniUniversité Claude Bernard Lyon 1
Stefan D. Anker
Stefan D. AnkerNational Institutes of Health
UDUlf DahlströmHeart Failure / Cardiomyopathy

Discussion

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Implication

High real-world adherence to guidelines in chronic HF when accounting for exceptions; leaves open standardization of acute HF therapy.

Key Points

  • To evaluate the adherence to European Society of Cardiology guidelines in the treatment of hospitalized and ambulatory patients with heart failure.
  • Analyzed data from 12,440 patients in the ESC Heart Failure Long-Term Registry
  • Assessed heterogeneity of treatments in acute heart failure
  • Evaluated drug treatment adherence in chronic heart failure
  • In chronic heart failure, drug treatment adheres largely to guidelines when considering reasons for non-adherence
  • Acute heart failure treatment shows substantial variability
  • Implications for developing more practical clinical guidelines in everyday care

Structured PICO

Are hospitalized or ambulatory patients with heart failure treated in accordance with European Society of Cardiology guidelines?

P
Population
12,440 hospitalized or ambulatory patients with acute or chronic heart failure from the ESC Heart Failure Long-Term Registry
I
Intervention
Treatment in accordance with European Society of Cardiology (ESC) guidelines
O
Outcome
Adherence to recommendations of current guidelines

Real-world data from a pan-European registry demonstrates that chronic heart failure treatment is largely adherent to ESC guidelines when accounting for valid reasons for non-adherence, though acute heart failure management remains highly heterogeneous.

Cite This Study

Maggioni et al. (2013) studied this question.

synapsesocial.com/papers/69d84bad8c03fbaff8beebd9https://doi.org/10.1093/eurjhf/hft134

Topics

Heart failureHFrEF treatmentHeart failure hospitalizationCardiac device therapyDual antiplatelet therapyStatin therapy
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Practical Recommendations for the Use of ACE Inhibitors, Beta-Blockers, Aldosterone Antagonists and Angiotensin Receptor Blockers in Heart Failure: Putting Guidelines into Practice2005 · 135 citations
  2. 2EuroHeart Failure Survey II (EHFS II): a survey on hospitalized acute heart failure patients: description of population2006 · 1,307 citations
  3. 3Adherence to Heart Failure Quality-of-Care Indicators in US Hospitals2005 · 271 citations
  4. 4Multicenter Prospective Observational Study on Acute and Chronic Heart Failure2013 · 201 citations
  5. 5ESC Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure 20122012 · 2,638 citations