February 1, 2002American Journal of Hypertension269 citationsOpen Access

Reproducibility of home, ambulatory, and clinic blood pressure: implications for the design of trials for the assessment of antihypertensive drug efficacy

GSGeorge S. StergiouPreventive Cardiology NBN. M. BaibasNational and Kapodistrian University of Athens AGAlexandra P. GantzarouAristotle University of Thessaloniki

Structured PICO

Does home blood pressure measurement improve reproducibility compared to clinic and ambulatory blood pressure measurement?

Intervention

Home blood pressure (HBP) measurement

Comparator

Clinic blood pressure (CBP) and ambulatory blood pressure (ABP) measurement

Outcome

Reproducibility of blood pressure measurementsurrogate

Home blood pressure monitoring offers superior reproducibility over clinic and ambulatory measurements, potentially reducing sample size requirements for antihypertensive drug trials.

Abstract

The study shows that HBP seems to have superior reproducibility compared with both CBP and ABP. In addition, HBP can improve the accuracy of antihypertensive drug trials, thereby reducing the sample size required.

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