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September 22, 2015Human Reproduction Update387 citationsOpen Access

Infertility and reproductive disorders: impact of hormonal and inflammatory mechanisms on pregnancy outcome

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SVSilvia VannucciniVCVicki L. CliftonIFIan S. Fraser

Key Points

  • To explore how hormonal and inflammatory mechanisms influence pregnancy outcomes in women with reproductive disorders.
  • Review of existing literature on inflammation, endocrinology, and metabolic mechanisms in reproductive health.
  • Identification of high-risk obstetric complications linked to reproductive disorders.
  • Reproductive disorders are linked to increased obstetric complications during pregnancy.
  • Need for specialized follow-ups for women identified as high risk for poor pregnancy outcomes.

Abstract

Reproductive disorders are common in women of childbearing age and rarely occur in isolation. Inflammatory, endocrine and metabolic mechanisms associated with these disorders are responsible for an increased incidence of obstetric complications. These patients should be recognized as 'high risk' for poor pregnancy outcomes and monitored with specialized follow-up. There is a real need for development of evidence-based recommendations about clinical management and specific obstetric care pathways for the introduction of prompt preventative care measures.

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Cite This Study

Vannuccini et al. (2015) studied this question.

synapsesocial.com/papers/69d8a8edce048d2571bed8echttps://doi.org/10.1093/humupd/dmv044
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