What question did this study set out to answer?

To summarize the dual physiological and pathological actions of reactive oxygen species and assess the roles of key organelles in cellular redox regulation.

January 1, 2012SHILAP Revista de lepidopterologíaOpen Access

Reactive Oxygen Species in Health and Disease

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Authors

AAAssim A. AlfaddaKing Abdulaziz City for Science and Technology RSReem M. SallamAin Shams University

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Implication

Narrative review outlines dual roles of reactive oxygen species in cellular physiology and disease, highlighting organelle-driven redox regulation.

Key Points

To summarize the dual physiological and pathological actions of reactive oxygen species and assess the roles of key organelles in cellular redox regulation.
Synthesized literature on the molecular generation, metabolism, and regulatory functions of reactive oxygen species across various cell types.
Evaluated contemporary research on organelle-specific redox control, focusing on the endoplasmic reticulum and mitochondria.
Identifies reactive oxygen species as cellular metabolic products that span a wide functional range from essential physiological regulators to mediators of tissue damage.
Establishes the mitochondria and the endoplasmic reticulum as the two primary cellular organelles driving reactive oxygen species generation and metabolic redox balance.

Cite This Study

Alfadda et al. (2012) studied this question.

synapsesocial.com/papers/69d8b93cce048d2571bedf32 https://doi.org/10.1155/2012/936486

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Implication

Narrative review outlines dual roles of reactive oxygen species in cellular physiology and disease, highlighting organelle-driven redox regulation.

Reactive Oxygen Species in Health and Disease

Discussion

Member takes

Implication

Key Points

Cite This Study

Reactive Oxygen Species in Health and Disease

Discussion

Member takes

Implication

Key Points

Cite This Study

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