Disease Progression in Cardiac Transthyretin Amyloidosis is Indicated by Serial Calculation of National Amyloidosis Centre Transthyretin Amyloidosis Stage

National Amyloidosis Centre ATTR stage predicts ongoing survival throughout the disease natural history in ATTR-CM, and an increase from NAC ATTR Stage I at diagnosis to a higher NAC ATTR stage predicts mortality throughout follow-up. Serial calculation of NAC ATTR stage suggests a more aggressive phenotype in V122I-hATTR-CM than in wtATTR-CM.