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August 1, 1999European Journal of Heart Failure245 citationsOpen Access

Is the Prognosis of Heart Failure Improving?

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JCJohn G.F. ClelandIGIslay GemmellAKAleem Khand

Key Points

  • The aim is to assess whether the prognosis of first-time heart failure admissions is improving over time.
  • Analyzed data on first admissions for heart failure over a defined period.

Structured PICO

Is the prognosis of patients with a first admission for heart failure improving with the increased use of ACE inhibitors?

P
Population
Patients with a first admission for heart failure
I
Intervention
Angiotensin converting enzyme (ACE) inhibitors
O
Outcome
Prognosis

Observational data suggests an improving prognosis for first-time heart failure admissions, temporally associated with increased ACE inhibitor utilization.

Limitations

  • A causal link cannot be proved from these data

Abstract

These data suggest that the prognosis of patients with a first admission for heart failure is improving. The timing of improvement coincides with the gradual increase in the use of angiotensin converting enzyme inhibitors for heart failure although a causal link cannot be proved from these data.

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Cite This Study

Cleland et al. (1999) studied this question.

synapsesocial.com/papers/69d8fc462c87b79b92d18a96https://doi.org/10.1016/s1388-9842(99)00032-x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Overview of randomized trials of angiotensin-converting enzyme inhibitors on mortality and morbidity in patients with heart failure. Collaborative Group on ACE Inhibitor Trials1995 · 1,539 citations
  2. 2Influence of concomitant disease on patterns of hospitalization in patients with heart failure discharged from Scottish hospitals in 19951998 · 134 citations
  3. 3Incidence of heart failure in eastern Finland: a population-based surveillance study1992 · 152 citations
  4. 4Regression Models and Life-Tables1972 · 39,703 citations
  5. 5Effect of Enalapril on Survival in Patients with Reduced Left Ventricular Ejection Fractions and Congestive Heart Failure1991 · 8,083 citations