LDHA-mediated metabolic reprogramming promoted cardiomyocyte proliferation by alleviating ROS and inducing M2 macrophage polarization

Yijin Chen; Yijin Chen; Guangkai Wu; Mengsha Li; Michael Hesse; Yusheng Ma; Wei Chen; Haoxiang Huang; Yu Liu; Wenlong Xu; Yating Tang; Hao Zheng; Chuling Li; Zhongqiu Lin; Guojun Chen; Wangjun Liao; Yulin Liao; Jianping Bin; Yanmei Chen; Yanmei Chen

doi:10.1016/j.redox.2022.102446

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Abstract

LDHA-mediated metabolic reprogramming promoted CM proliferation by alleviating ROS and inducing M2 macrophage polarization, indicating that LDHA might be an effective target for promoting cardiac repair post-MI.

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Chen et al. (2022) studied this question.

synapsesocial.com/papers/69d963a900ab073a27836542 https://doi.org/10.1016/j.redox.2022.102446

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LDHA-mediated metabolic reprogramming promoted cardiomyocyte proliferation by alleviating ROS and inducing M2 macrophage polarization

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Abstract

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LDHA-mediated metabolic reprogramming promoted cardiomyocyte proliferation by alleviating ROS and inducing M2 macrophage polarization

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Abstract

Discussion

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