Why the study?
Does catecholamine stress affect diastolic function and myocardial energetics in obesity?
Does catecholamine stress affect diastolic function and myocardial energetics in obesity?
Deranged myocardial energetics during inotropic stress may contribute to diastolic dysfunction in obesity.
May implicate energetics in stress-induced diastolic dysfunction in obesity; hypothesis-generating for metabolic therapies.
In obesity, cardiac energetics are further deranged during inotropic stress, in association with continued diastolic dysfunction. Myocardial energetics may play a key role in the impairment of diastolic function in obesity.
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Rider et al. (2012) studied this question.
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