Why the study?
Does etanercept reduce the rate of death or hospitalization in patients with chronic heart failure?
Does etanercept reduce the rate of death or hospitalization in patients with chronic heart failure?
Etanercept does not provide a clinically relevant benefit for reducing death or hospitalization in patients with chronic heart failure.
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Avoid etanercept in chronic heart failure; RCT confirms no reduction in death or hospitalization.
Mann et al. (2004) studied this question.