March 21, 2023SHILAP Revista de lepidopterologíaOpen Access

Relationship Between Left Ventricular Hypertrophy and Diabetes Is Likely Bidirectional: A Temporality Analysis

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Why the study?

The temporal relationship between type 2 diabetes and left ventricular hypertrophy was not well established.

Is there a bidirectional temporal relationship between type 2 diabetes and left ventricular hypertrophy in middle-aged adults?

Population

1000 adults with baseline fasting glucose/T2DM and echocardiographic data

Comparison

Baseline LVH vs normal LVMI, and baseline T2DM vs non-T2DM

Design

Longitudinal cohort study

Follow-up

9.4 years on average

Authors

JLJiali LvShandong University YLYang LiuWuhan University YYYinkun YanGeneral / Preventive / Lipids

Discussion

Member takes

Implication

Association may support closer monitoring in at-risk adults; leaves open causal direction for prospective trials.

Structured PICO

Is there a bidirectional temporal relationship between type 2 diabetes and left ventricular hypertrophy in middle-aged adults?

Population

1000 adults (682 White individuals and 318 Black individuals; 41.1% men; mean age, 36.2 years at baseline) who had data on fasting glucose/T2DM, left ventricular mass index (LVMI), and relative wall thickness.

Outcome

Temporal sequence and bidirectional incidence of T2DM and LVH/cardiac geometry patterns (LVMI, relative wall thickness) over 9.4 years on averagesurrogate

The temporal relationship between type 2 diabetes and left ventricular hypertrophy is bidirectional, with the pathway from LVH to diabetes appearing stronger than the reverse.

Cite This Study

Lv et al. (2023) studied this question.

synapsesocial.com/papers/69daa232615cc0c8eaa3c366 https://doi.org/10.1161/jaha.122.028219

Topics

Hypertension management Echocardiography

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