Metabolomics combined with functional evaluation may serve as an innovative tool for staging heart failure and investigating metabolic perturbations.
The results demonstrate the suitability of metabolomics in combination with functional evaluation techniques in HF staging. This innovative tool should facilitate investigation of perturbed metabolic pathways in HF and their correlation with the impairment of myocardial function.
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Deidda et al. (2015) studied this question.
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