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April 11, 1996New England Journal of Medicine1,777 citations

Effect of the Angiotensin-Converting–Enzyme Inhibitor Benazepril on the Progression of Chronic Renal Insufficiency

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GMGiuseppe MaschioDADaniele AlbertiGJG. Janin

Key Points

  • Assess the therapeutic impact of the ACE inhibitor benazepril on slowing the progression of chronic renal insufficiency in patients with various renal diseases.
  • Evaluated the effect of benazepril administration in patients presenting with chronic renal insufficiency arising from various underlying renal diseases.

Structured PICO

Does benazepril prevent the progression of renal insufficiency in patients with chronic renal insufficiency?

P
Population
Patients with chronic renal insufficiency and various renal diseases
I
Intervention
Benazepril (Angiotensin-Converting-Enzyme Inhibitor)
O
Outcome
Progression of renal insufficiency

Benazepril protects against the progression of chronic renal insufficiency in patients with various renal diseases.

Abstract

Benazepril provides protection against the progression of renal insufficiency in patients with various renal diseases.

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Cite This Study

Maschio et al. (1996) studied this question.

synapsesocial.com/papers/69dac5948988aeabbe687b9bhttps://doi.org/10.1056/nejm199604113341502
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