November 25, 2010Expert Review of Cardiovascular Therapy
Antihypertensive and organ-protective effects of benazepril
Why the study?
Does benazepril improve blood pressure control, renal outcomes, and cardiovascular morbidity/mortality in patients with hypertension?
Population
Patients with hypertension (including systolic hypertension) and potential for atrial fibrillation
Design
Review
Authors
Discussion
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Member takes
Implication
Benazepril may support hypertension management with renal and CV benefits; leaves open need for contemporary RCTs.
Structured PICO
Does benazepril improve blood pressure control, renal outcomes, and cardiovascular morbidity/mortality in patients with hypertension?
P
Population
Patients with hypertension (including systolic hypertension) and potential for atrial fibrillation
I
Intervention
Benazepril alone or in combination with hydrochlorothiazide or amlodipine
O
Outcome
Blood pressure control, renal outcomes, and cardiovascular morbidity and mortality
Benazepril is an effective antihypertensive agent that offers additional renal and cardiovascular protective benefits, particularly when used in combination therapy.
Cite This Study
Barrios et al. (2010) studied this question.