Why the study?
Does benazepril reduce blood pressure in patients with mild to moderate hypertension compared to hydrochlorothiazide or placebo?
Population
206 patients with mild to moderate hypertension
Comparison
Benazepril at a dose of 2, 5, 10, or 20 mg once… vs Hydrochlorothiazide 25 mg or placebo once daily…
Design
RCT, randomized
Follow-up
4 weeks
Authors
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Supports benazepril as a non-thiazide alternative; extends RCT evidence for ACEIs in mild-moderate hypertension.
Does benazepril reduce blood pressure in patients with mild to moderate hypertension compared to hydrochlorothiazide or placebo?
Benazepril 20 mg once daily is as effective as hydrochlorothiazide 25 mg in lowering blood pressure in patients with mild to moderate hypertension.
Moser et al. (1991) studied this question.
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