Why the study?
Are blunted left atrial strain and reserve during exercise associated with worse cardiopulmonary performance and outcomes in heart failure patients?
Are blunted left atrial strain and reserve during exercise associated with worse cardiopulmonary performance and outcomes in heart failure patients?
Impaired left atrial dynamics during exercise are associated with worse cardiopulmonary performance and outcomes in heart failure patients, regardless of LVEF.
Answers are grounded in this paper and cite their sources.
May refine HF risk stratification during exercise; hypothesis-generating, requiring prospective validation before practice change.
In HF, LA dynamics may play a key role in exercise CO increase due to an impaired forward (left ventricular filling) and backward (right ventricular to pulmonary circulation uncoupling) combination of mechanisms, irrespective of LVEF. The blunted LA strain and LA sra reserve during exercise are associated with a worse cardiopulmonary performance and outcome.
No takes yet. Share an insight, caveat, or question.
Sugimoto et al. (2020) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: