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November 1, 2022SHILAP Revista de lepidopterologíaOpen Access

Iron stores in steady‐state sickle cell disease children accessing care at a sickle cell disease clinic in Kumasi, Ghana: A cross‐sectional study

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Authors

EAErnest AmanorAKAlexander KwartengALAmma Larbi

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Overview

Cross-sectional study finds high rates of elevated iron stores in children with steady-state sickle cell disease, suggesting regular monitoring after multiple blood transfusions.

Key Points

  • To evaluate iron stores and identify indicators of iron overload in children with steady-state sickle cell disease.
  • Conducted a cross-sectional study among pediatric patients with steady-state sickle cell disease receiving outpatient clinic care in Kumasi, Ghana.
  • Assessed hemotransfusion history and measured red cell indices to evaluate risk of elevated iron stores.
  • Elevated iron stores occurred at a high magnitude among pediatric patients in steady-state.
  • Red cell indices provided actionable indicators for assessing the risk of elevated iron stores.
  • Patients with chronic hemotransfusion or at least three transfusions per year demonstrated high risk for elevated iron levels.

Cite This Study

Amanor et al. (2022) studied this question.

synapsesocial.com/papers/69dbc45350e1971baba3c925https://doi.org/10.1002/hsr2.934
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Also Consider

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  1. 1Assessing Liver and Iron Markers in Steady State Pediatric SCD Patients to Ascertain the Hepatic Consequences of Hemotransfusion: A Case‐Control Study in Ghana2026
  2. 2The burden of iron overload in sickle cell disease: insights from South Carolina, USA.2025 · 1 citations
  3. 3Serum iron Profile of Patients with Sickle Cell Disease and its Association with Socio-demographic Characteristics and Duration of Diagnosis2024
  4. 4A Study of the Clinical Profile of Iron Deficiency Anemia in Children With Sickle Cell Disease in a Tertiary Care Center2024
  5. 5Prevalence of iron deficiency among youth with sickle cell disease2025