Short-term and Long-term Postoperative Safety of Off-Pump versus On-Pump Coronary Artery Bypass Grafting for Coronary Heart Disease: A Meta-analysis for Randomized Controlled Trials

Taobo Luo; Yiming Ni

doi:10.1055/s-0035-1544232

March 24, 2015The Thoracic and Cardiovascular Surgeon

Short-term and Long-term Postoperative Safety of Off-Pump versus On-Pump Coronary Artery Bypass Grafting for Coronary Heart Disease: A Meta-analysis for Randomized Controlled Trials

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Why the study?

Does off-pump CABG improve short-term and long-term postoperative safety compared to on-pump CABG in patients with coronary heart disease?

Key Points

To compare the short-term and long-term postoperative safety and clinical outcomes between off-pump and on-pump coronary artery bypass grafting in patients with coronary heart disease.
Conducted a meta-analysis pooling evidence from randomized controlled trials comparing off-pump against on-pump coronary artery bypass grafting.
Evaluated short-term postoperative safety profiles alongside long-term outcomes, specifically repeat revascularization rates.
Short-term postoperative safety does not differ between off-pump and on-pump coronary artery bypass grafting groups (specific effect sizes and p-values not reported).
Off-pump coronary artery bypass grafting results in a higher rate of repeat revascularization during long-term follow-up compared with on-pump surgery (specific numerical rates not reported).

Structured PICO

Does off-pump CABG improve short-term and long-term postoperative safety compared to on-pump CABG in patients with coronary heart disease?

P

Population

Patients with Coronary Heart Disease (CHD)

I

Intervention

Off-pump coronary artery bypass grafting (CABG)

C

Comparator

On-pump coronary artery bypass grafting (CABG)

O

Outcome

Short-term and long-term postoperative safetysafety

While short-term safety is similar, off-pump CABG is associated with a higher long-term need for revascularization compared to on-pump CABG.

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Implication

Short-term safety equivalence supports individualized CABG choice; challenges off-pump preference by confirming higher long-term revascularization.

Abstract

Short-term postoperative safety was similar between off-pump and on-pump CABG. A high revascularization rate was the drawback of off-pump CABG for CHD patients in long-term follow-up.

Discussion

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Cite This Study

Luo et al. (2015) studied this question.

synapsesocial.com/papers/69dbeb1f8fbc15f99e68462c https://doi.org/10.1055/s-0035-1544232

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Short-term and Long-term Postoperative Safety of Off-Pump versus On-Pump Coronary Artery Bypass Grafting for Coronary Heart Disease: A Meta-analysis for Randomized Controlled Trials

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Short-term and Long-term Postoperative Safety of Off-Pump versus On-Pump Coronary Artery Bypass Grafting for Coronary Heart Disease: A Meta-analysis for Randomized Controlled Trials

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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