Do left ventricular remodelling and longitudinal function distinguish low-flow from normal-flow preserved ejection fraction low-gradient severe aortic stenosis and predict survival?
Low-flow, low-gradient severe aortic stenosis with preserved ejection fraction is characterized by adverse LV remodeling and worse survival compared to normal-flow low-gradient AS.
Preserved ejection fraction, LFLG AS patients exhibit marked concentric remodelling and impaired longitudinal functional-features that predict their poor long-term survival. Normal-flow, low-gradient AS patients have outcomes similar to moderate AS.
Mehrotra et al. (Tue,) studied this question.