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June 1, 2015CellOpen Access

A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development

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Authors

WTWalfred W. C. TangUniversity of CambridgeSDSabine DietmannWashington University in St. LouisNINaoko IrieSocial Insurance Saitama Chuo Hospital

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Tang et al. (2015) studied this question.

synapsesocial.com/papers/69dc91168dd2fd42bd1333f6https://doi.org/10.1016/j.cell.2015.04.053
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Dynamics of Genome-wide DNA Methylation Reprogramming in Mouse Primordial Germ Cells2012 · 1,014 citations
  2. 2Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming2013 · 171 citations
  3. 3Genome-Wide Analysis of DNA Methylation Dynamics during Early Human Development2014 · 264 citations
  4. 4DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages2006 · 219 citations