What question did this study set out to answer?

To determine whether circulating levels of C-reactive protein predict the future onset of hypertension and evaluate the role of inflammation in high blood pressure.

December 9, 2003JAMA

C-Reactive Protein and the Risk of Developing Hypertension

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Why the study?

Are C-reactive protein levels associated with the future development of hypertension?

Key Points

To determine whether circulating levels of C-reactive protein predict the future onset of hypertension and evaluate the role of inflammation in high blood pressure.
Assessed baseline plasma C-reactive protein levels in relation to the subsequent incidence of hypertension over follow-up.
Higher baseline C-reactive protein levels show a positive association with the future risk of developing hypertension.
The link between biomarker elevation and high blood pressure indicates that hypertension pathogenesis involves inflammatory pathways.

Structured PICO

Are C-reactive protein levels associated with the future development of hypertension?

Intervention

C-reactive protein levels

Outcome

future development of hypertension

C-reactive protein levels are associated with the future development of hypertension, suggesting it is in part an inflammatory disorder.

Implication

Suggests inflammatory contribution to hypertension; leaves open CRP utility for risk stratification or prevention trials.

Abstract

C-reactive protein levels are associated with future development of hypertension, which suggests that hypertension is in part an inflammatory disorder.

Discussion

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Cite This Study

Howard D. Sesso (2003) studied this question.

synapsesocial.com/papers/69dcc93c5f911386753594d9 https://doi.org/10.1001/jama.290.22.2945

Topics

Hypertension management

View Full Paper

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Implication

Suggests inflammatory contribution to hypertension; leaves open CRP utility for risk stratification or prevention trials.

Abstract

C-reactive protein levels are associated with future development of hypertension, which suggests that hypertension is in part an inflammatory disorder.

C-Reactive Protein and the Risk of Developing Hypertension

Key Points

Structured PICO

Implication

Abstract

Discussion

Cite This Study

Topics

C-Reactive Protein and the Risk of Developing Hypertension

Key Points

Structured PICO

Implication

Abstract

Discussion

Cite This Study

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Topics

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