May 1, 2001Journal of Hypertension
Is C-reactive protein an independent risk factor for essential hypertension?
Why the study?
Are elevated circulating levels of C-reactive protein independently associated with essential hypertension in adults?
Population
300 subjects ≥ 30 years old from the general community of Bucaramanga, Colombia
Comparison
Higher quartiles of circulating C-reactive protein vs Lowest quartile of circulating C-reactive protein
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Supports CRP-hypertension link after adjustment; leaves open causality and needs prospective confirmation before practice implications.
Structured PICO
Are elevated circulating levels of C-reactive protein independently associated with essential hypertension in adults?
P
Population
300 subjects ≥ 30 years old from the general community of Bucaramanga, Colombia
I
Intervention
Higher quartiles of circulating C-reactive protein (CRP)
C
Comparator
Lowest quartile of circulating C-reactive protein (CRP)
O
Outcome
Arterial blood pressure (prevalence of hypertension)surrogate
Elevated C-reactive protein levels are independently associated with a higher prevalence of essential hypertension, suggesting inflammation may play a role in its development.
Limitations
- cross-sectional nature of the study
Cite This Study
Bautista et al. (2001) studied this question.