Key result
Hypertensive patients had higher mean C-reactive protein levels (2.923 mg/L) compared to normotensive patients (1.058 mg/L), though elevated CRP was not associated with hypertensive complications.
Why the study?
Does baseline C-reactive protein level predict the development of hypertensive complications at 6 months in adult patients?
Observational (n=112)
No
Does baseline C-reactive protein level predict the development of hypertensive complications at 6 months in adult patients?
Absolute Event Rate: 2.923% vs 1.058%
Baseline CRP is elevated in hypertensive patients compared to normotensive individuals but does not predict the short-term development of hypertensive complications.
Baseline CRP does not predict 6-month hypertensive complications; leaves open its prognostic value in prospective studies.
Background and objective : C-reactive protein (CRP) is a well-known inflammatory biomarker and is associated with cardiovascular risk. Our objective was to see whether it is also associated with hypertension and its complications.Methodology : This prospective observational study was carried out in general outpatient department (OPD) of a tertiary level hospital on a total of 112 patients, among them 71 were hypertensive and 41 were normotensive. Baseline CRP was measured in all subjects and followed them up to six months to see any association between the level of CRP and hypertensive complications.Results : It is found that mean CRP was 2.923 (± 0.294) in hypertensive subjects and 1.058 (± 0.330) in normotensive subjects. No association is found between level of CRP and hypertensive complications.Conclusion : CRP is raised in hypertension. But it is not established that its level can predict the complication of hypertension.Bangladesh Crit Care J March 2018; 6(1): 3-6
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Alam et al. (2018) conducted an observational in Hypertension (n=112). Hypertension vs. Normotension was evaluated on Mean C-reactive protein (CRP) level. Hypertensive patients had higher mean C-reactive protein levels (2.923 mg/L) compared to normotensive patients (1.058 mg/L), though elevated CRP was not associated with hypertensive complications.
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