Why the study?
What is the optimal target INR for oral anticoagulant therapy in patients with mechanical heart valves?
Population
Patients with mechanical/prosthetic heart valves
Design
Guideline
Authors
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Clinicians should target INR 3.0-4.0 for mechanical valves; reinforces Level 1 guideline standards.
What is the optimal target INR for oral anticoagulant therapy in patients with mechanical heart valves?
For patients with mechanical heart valves, a target INR of 3.0 to 4.0 is recommended to maintain optimal anticoagulation.
Cannegieter et al. (1995) studied this question.
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